Gender-Based Differences in Hematological and CD4+ T- Lymphocyte Counts among HIV-Patients in Ido-Ekiti


Esan A.J.


Full Length Research Paper I Published September, 2016


Journal of Medical and Biological Science Research Vol. 2 (9), pp. 143-148



The aim was to determine gender-based differences in some hematological and immunological parameters among Human Immunodeficiency Virus (HIV)-patients on treatment and treatment naïve in Ekiti. Differences in prevalence and severity of HIV/AIDS infection between males and females remain complex and controversial; this may vary with time in the same location during the course of the epidemic. A total of 400 HIV infected participants were recruited for the study. Four milliliters (4ml) of blood samples were collected into K2 EDTA bottles for the analysis of hematological and immunological parameters. Two hundred and seventy seven (277) were females (146 on highly active antiretroviral therapy (HAART) and 131 HAART naïve) while 123 were males (54 on HAART and 69 HAART naïve). Hematological and immunological parameters were statistical significantly higher in HAART patients. Female are at higher risk of HIV infection compared to their male counterparts, this study demonstrated that significant hematological and immunological differences exist between male and female initiating HAART and HAART naïve.

Key words: Sex, HIV-Patients, Hematological and Immunological Parameters.

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