Prevalence of Asymptomatic Bacteriuria in a Sub-population of Tertiary Female Students: Antimicrobial Resistance Patterns and Group-specific Risk Factors
Alex Boye, Felicia Pokuaa Dwomoh, Martin Tangnaa Morna,
Richard Kwabena Dadzie Ephraim and Samuel Essien-baidoo
Full Length Research Paper I Published April, 2016
Journal of Medical and Biological Science Research Vol.
2 (4), pp. 56-64
ABSTRACT
Asymptomatic bacteriuria (ASB) is a major risk factor for
urinary tract infections in most-at-risk populations. This
study determined ASB positivity, common uropathogens,
antimicrobial resistance (AMR) and risk factors of ASB among
tertiary female students. A cross-sectional study was
conducted on randomly recruited resident female students (n
= 156). After questionnaire completion, urine samples were
collected on appointment basis and routinely analyzed.
Dipstick, microscopy, and urine culture methods were used to
establish ASB positivity. Disk diffusion method was used to
determine AMR. From 156 urine samples, 15 (9.6%) tested
positive for ASB (single organism count > 105/mL
from two consecutively voided mid-stream urine). A total of
24 isolates comprising: coagulase negative Staphylococci (CoNS)
9 (37.5%), Klebsiella pneumonia 6 (25.0%),
Staphylococcus aureus 5 (20.8%), Escherichia coli
2 (8.3%), and Serratia marcescens 2 (8.3%). All
isolates exhibited 100% susceptibility to nitrofurantoin and
gentamicin but 100% resistance to ampicillin. CoNS were 100%
sensitive to all antibiotics except cefuroxime and
ampicillin. S. aureus and K. pneumonia
exhibited acquired multidrug resistance to antibiotics
belonging to ≥ 5 chemical classes. ASB positivity was 9.6%;
nitrofurantoin and gentamicin were the most effective
antibiotics, and ASB may be associated with poor personal
hygiene.
Key words: Antimicrobial resistance, Bacteriuria,
Multidrug resistance, Uropathogens and Ghana.
- Journal of Agricultural Science and Food Technology (JASFT)
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- Pearl Journal of Management, Social Science and Humanities (PJMSSH)