Diagnosis of Plasmodium Falciparum Infection Using Immuno-Chromatography Test in Blood and Urine of Sudanese People in Elgadaraf State

 

Wahaj M Mohammed, Jehan AAlhaj, Abelwahab A Aldaw and Ahmed S Kabbashi
 

Short Communcation I Published August, 2019

 

Journal of Medical and Biological Science Research Vol. 5 (1), pp. 1-3.

 

ABSTRACT

Malaria Plasmodium falciparum rapid card test (QDx rapid malaria test) is an immunochromatographic test that detects the presence of malaria antigen (HRP-2) in blood samples. These malaria antigens are also released in the urine. This study was conducted to determine the sensitivity, specificity of the QDx Rapid Malaria test for the diagnosis of malaria in blood and urine. Blood and urine specimens were obtained from 90 malaria blood smear-positive cases (test samples) and 90 malaria negative cases (controls). The urine and blood specimen was collected for QDx rapid malaria test. Using microscopy as the gold standard, the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of the QDx rapid malaria test for urine and blood were calculated. The sensitivity of QDx rapid malaria test for malaria parasite detection was 92.2% for blood and 7.7% for urine. Rapid malaria test processed with urine may be unuseful in detecting falciparum malaria antigens.

Key words: Rapid malaria test, HRP-2, Urine, Sensitivity and Specificity.

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