Evaluation of Iron Profile in Sudanese with Rheumatoid Arthritis
Noha Mohamed Saeed, Salih A. Elmahdi, Gadalla Modawe and
AbdElkarim A. Abdrabo
Full Length Research Paper I Published March, 2016
Journal of Medical and Biological Science Research Vol.
2 (3), pp. 44-48
ABSTRACT
Anemia adds considerably to the morbidity in patients with
rheumatoid arthritis (RA). Iron has many important functions
in human body. This study aimed to evaluate the level of
blood indices, serum Iron and Total Iron Binding Capacity (TIBC)
and their correlation with durations and complications of
disease. This is cross-sectional study involved 48 patients
with rheumatoid arthritis disease. The serum level of iron
and total TIBC were estimated by the automated chemistry
analyzer (COBAS-plus 400), blood indices by automated
hematology analyzer (Sysmex). The analysis of the results
indicated that the means level of iron, TIBC, hemoglobin,
mean cell hemoglobin (MCH), mean cell hemoglobin
concentration (MCHC) were significantly lower than the
reference value, while hematocrit (HCT) results revealed
insignificant change.
Positive correlations were found in MCH, HCT and duration of
disease. All hematology parameters levels were insignificantly
correlated with complication of disease. The results
observed that the levels of serum iron, TIBC, MCH and Hb was
significantly decreased in patients with Rheumatoid
arthritis when compared to reference value. Insignificant
correlation observed between level of these elements and
complication of RA disease, and significantly increases
level of HCT, MCH in long duration patient group.
Key words: Rheumatoid, Iron, TIBC and Sudan.
- Journal of Agricultural Science and Food Technology (JASFT)
- Journal of Medical and Biological Science Research (JMBSR)
- Journal of Scientific Research and Essays (JSRE)
- Research Journal of Educational Studies and Review (RJESR)
- Journal of Physical Science and Environmental Studies (JPSES)
- Research Journal of Engineering and Technology (RJET)
- Pearl Journal of Management, Social Science and Humanities (PJMSSH)