Assessment of Calcium Phosphorus and Parathyroid Hormone in Sudanese Patient with Renal Transplantation

 

Ohood Abass Ibrahim, Gad Allah Modawe and AbdElkarim A. Abdrabo
 

 

Research Paper I Published January,2016

 

Journal of Medical and Biological Science Research Vol. 2 (1), pp. 1-4

 

ABSTRACT

Kidney transplantation is the treatment of choice for end-stage renal disease (ESRD). Restoration of renal function after kidney transplantation rectifies many of the disturbances that lead to renal osteodystrophy, bone disease and cardiovascular disease and an increased risk of morbidity and mortality. Identifying patients at risk and evaluating for this complication is imperative because early intervention may slow or arrest the progression of both bone and cardiac disease. Helping physician and renal transplant center to creating a successful treatment plan. The objective of this study was to evaluate calcium, phosphorus and parathyroid hormone concentrations in renaltransplantation in Sudanese patient. This study was case control hospital based study, conducted in Sudanese renal transplantation association, Khartoum state. During June to July 2013.The study involved a control group (n= 50) matched for age with a renaltransplantation patient (n= 50). The ages ranged in both groups were 20 to 65 years. Serum calcium and phosphorus was measured by spectrophotometric methods using chemistry analyzer (cobas c311 analyzer, Germany). While Parathyroid hormone (PTH) levels were determined by electrochemiluminescence using hormone analyzer (cobas e411 analyzer, Germany). The (Mean±SD) of Ca, PTH and posphorus in patient respectively were (9.87±0.52mg/dl, 56.45±26.21 pg/ml,3.36±0.55 mg/dl).While (Mean±SD) of control group was (9.76±0.59mg/dl, 56.02±15 pg/ml,42.3.66±0.43 mg/dl).There was significant decrease of serum phosphorus (p0.003) in subjects with ESRD while Ca and PTH showed no significant difference. This study concluded that, ESRD significant decrease of serum phosphorus, while Ca and PTH were normal in the study.

Key words: Calcium, Phosphorus, PTH, Renal failure, Sudan.

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